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Vaginal insufflation is not considered a systemic ozone treatment since, unlike venous infusion and rectal insufflation, there is no direct involvement of the bloodstream or, although the surface of the vaginal area is considerably large, the local effects prevail over systemic ones. Unlike the rectal technique, in these cases it is necessary to use relatively high doses of ozone that are mainly able to destroy the fungi or other parasites present in the area.

It is clear that, by preliminarily evaluating the sensitivity of the patients, the concentration must be gradually increased even beyond 60-70 µg / ml O3 / O2 always ensuring the tolerability of the subject to be treated with volumes ranging from 50 to 200 ml. 6 to 15 sessions are sufficient followed by a further 5-10 weekly sessions at lower concentrations (30-50 µg / ml O3 / O2) to obtain optimal results.

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